10 Key Reasons that scientists use ESCHERICHIA COLI as a Model Organism

Why ESCHERICHIA COLI as a Model Organism in Biotechnology?

                  Scientists says E.coli as a Molecular Biologist tool Box

There are following reasons that E.coli is used widely in experiments:

1. E.coli is a Gram negative Bacillus, generally harmless in nature for human beings.
2. The rod shape bacterium which is found in the lower intestine of warm blooded animals shows fast growth in culture media. Stains make colony and shows purity in easiest way.
3. The third and foremost important reason is the well understood genetic and genomics knowledge. Its genome sequenced in 1997, one of the earliest sequenced genome sequenced in the history.
4. E.coli based biosensors are helpful to identify the genes of targets like biotic or abiotic traits controlling genes.
5. Its temperature requirement under invivo reactions are similar to the human beings.
6. E.coli can grow with or without the availability of oxygen.
7. Rarely unwanted mutations appeared in cultures.
8. It shows rapid reproduction with small in size. About 2 billion copies from a single cell and 4.5 to 5.5 Mbps genome size.
9. The presence of extraordinary Plasmids with multiple characters.
10. It has simple nutritional requirements as compared to others.